scDiffCom 1.2.0

• run_interaction_analysis() now uses seurat_layer argument instead of seurat_slot to be consistent with Seurat (>= 5.0.0)
• Clean internal data dependencies and remove explicit call to SingleCellSignalR::LRdb
• Fix broken links in README
• Prepare for CRAN submission

scDiffCom 1.1.0

• Allow to use a custom LRI database

scDiffCom 1.0.0

01-11-2023

• Prepare for CRAN release
• Update links to the Nature Aging paper

scDiffCom 0.2.4

11-04-2023

• Change default red-green colors in plots
• Improve README and website

scDiffCom 0.2.3

08-05-2022

• Remove mouse and rat LRIs with “homolog_orthology_confidence” of 0, but only if they are not already provided directly by one of the “source database”
• Remove some miss-curated LRIs

scDiffCom 0.2.2

11-04-2022

• Compute (permutation-based) p-values and logFC for each ligand and receptor gene independently

scDiffCom 0.2.1

20-01-2022

• Fix a bug that appeared when ‘seurat_object[[]]’ contained a column named ‘cell_id’

scDiffCom 0.2.0

24-11-2021

• New function BuildShiny() that creates a shiny app from the results
• New function ReduceGO() to reduce GO terms by semantic similarity

scDiffCom 0.1.0.9000

09-11-2021

• A rat LRI database (LRI_rat) has been added (based on orthology conversion)
• run_interaction_analysis() accepts rat as species parameter
• LRI datasets have a reduced size
• Dataset gene_ontology_level is now available as data (instead of internal data)

scDiffCom 0.1

04-07-2021

• All steps of run_interaction_analysis have been tested
• All exported functions have been tested
• LRI databases have been curated
• Complete roxygen-based documentation
• Vignette contains the main functionalities

scDiffCom 0.0.0.9000

• Added a NEWS.md file to track changes to the package.
• Added the first proper documentation
• Added the first version of the vignette