fig:quick-pbmc-corrected fig:tsne-pbmc-uncorrected fig:tsne-pbmc-rescaled fig:tsne-pbmc-residuals fig:tsne-pbmc-corrected fig:multi-pbmc-corrected fig:heat-after-mnn fig:rand-after-mnn fig:mnn-delta-var-pbmc fig:pancreas-mnn-delta fig:pancreas-mnn-delta2 fig:pbmc-marker-blocked fig:seger-beta-ins-raw fig:seger-beta-ins-corrected fig:tsne-initial fig:heat-cluster-label fig:md-embryo fig:mds-embryo fig:bcvplot fig:qlplot fig:allantois-dispersion fig:exprs-unique-de-allantois fig:exprs-unique-de-allantois-more fig:between-label-dge fig:proxy-ambience fig:abplotbcv fig:abplotql fig:unref-pbmc-filtered-var fig:unref-filtered-pbmc-variance fig:unref-filtered-pbmc-tsne fig:unref-filtered-pbmc-merged-tsne fig:tsne-pancreas-rescaled fig:tsne-pancreas-mnn fig:tsne-pancreas-mnn-many fig:tsne-pancreas-mnn-donor fig:tsne-pancreas-mnn-donor-all fig:unref-umap-merged-hsc fig:unref-umap-traj-hsc fig:unref-umap-traj-hsc2 fig:unref-pijuan-var-1 fig:unref-pijuan-var-2 fig:unref-pijuan-var-3 fig:unref-pijuan-tsne integrating-datasets motivation quick-start slower-setup no-correction linear-regression by-rescaling-the-counts by-fitting-a-linear-model mnn-correction further-options correction-diagnostics motivation-1 mixing-between-batches preserving-biological-heterogeneity mnn-specific-diagnostics using-corrected-values background for-within-batch-comparisons after-blocking-on-the-batch for-between-batch-comparisons multi-sample-comparisons motivation-2 setting-up-the-data creating-pseudo-bulk-samples performing-the-de-analysis putting-it-all-together looping-across-labels cross-label-meta-analyses testing-for-between-label-differences ambient-problems background-1 filtering-out-affected-degs by-estimating-ambient-contamination with-prior-knowledge without-an-ambient-profile subtracting-ambient-counts differential-abundance overview performing-the-da-analysis composition-effects background-2 assuming-most-labels-do-not-change removing-the-offending-labels testing-against-a-log-fold-change-threshold comments-on-interpretation de-da-duality sacrificing-differences human-pbmcs-10x-genomics introduction data-loading quality-control normalization variance-modelling dimensionality-reduction clustering data-integration merged-pancreas introduction-1 the-good the-bad the-ugly merged-hsc introduction-2 data-loading-1 setting-up-the-merge merging-the-datasets combined-analyses chimeric-mouse-embryo-10x-genomics introduction-3 data-loading-2 quality-control-1 normalization-1 variance-modelling-1 merging clustering-1 dimensionality-reduction-1