Bioconductor 3.22 Released

RTNsurvival

This is the released version of RTNsurvival; for the devel version, see RTNsurvival.

Survival analysis using transcriptional networks inferred by the RTN package


Bioconductor version: Release (3.22)

RTNsurvival connects gene regulatory network activity with patient survival. Using regulons inferred by the RTN package, it computes single-sample differential Enrichment Scores (dES) and relates regulon activity patterns to survival outcomes. The package supports both Cox proportional hazards models and Kaplan–Meier analyses, allowing users to identify regulons associated with prognosis and to stratify cohorts based on regulon activity.

Author: Clarice S. Groeneveld, Vinicius S. Chagas, Mauro A. A. Castro

Maintainer: Clarice Groeneveld <clari.groeneveld at gmail.com>, Mauro A. A. Castro <mauro.a.castro at gmail.com>

Citation (from within R, enter citation("RTNsurvival")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RTNsurvival")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RTNsurvival")
RTNsurvival: multivariate survival analysis using transcriptional networks and regulons. HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews GeneRegulation, GeneSetEnrichment, GraphAndNetwork, NetworkEnrichment, NetworkInference, Software, Survival
Version 1.34.1
In Bioconductor since BioC 3.6 (R-3.4) (8.5 years)
License Artistic-2.0
Depends R (>= 4.4.0), RTN(>= 2.32), RTNduals(>= 1.32), methods
Imports survival, RColorBrewer, grDevices, graphics, stats, utils, scales, data.table, egg, ggplot2, pheatmap, dunn.test
System Requirements
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Suggests knitr, rmarkdown, BiocStyle, RUnit, BiocGenerics
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RTNsurvival_1.34.1.tar.gz
Windows Binary (x86_64) RTNsurvival_1.34.0.zip
macOS Binary (x86_64) RTNsurvival_1.34.0.tgz
macOS Binary (arm64) RTNsurvival_1.34.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/RTNsurvival
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RTNsurvival
Bioc Package Browser https://code.bioconductor.org/browse/RTNsurvival/
Package Short Url https://bioconductor.org/packages/RTNsurvival/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.22 Source Archive