PERSUADE: Parametric Survival Model Selection for Decision-Analytic Models

Provides a standardized framework to support the selection and evaluation of parametric survival models for time-to-event data. Includes tools for visualizing survival data, checking proportional hazards assumptions (Grambsch and Therneau, 1994, <doi:10.1093/biomet/81.3.515>), comparing parametric (Ishak and colleagues, 2013, <doi:10.1007/s40273-013-0064-3>), spline (Royston and Parmar, 2002, <doi:10.1002/sim.1203>) and cure models, examining hazard functions, and evaluating model extrapolation. Methods are consistent with recommendations in the NICE Decision Support Unit Technical Support Documents (14 and 21 <https://sheffield.ac.uk/nice-dsu/tsds/survival-analysis>). Results are structured to facilitate integration into decision-analytic models, and reports can be generated with 'rmarkdown'. The package builds on existing tools including 'flexsurv' (Jackson, 2016, <doi:10.18637/jss.v070.i08>)) and 'flexsurvcure' for estimating cure models.

Version: 0.1.2
Depends: R (≥ 4.1.0)
Imports: data.table, flexsurv, flexsurvcure, ggplot2, muhaz, rmarkdown, rms, sft, stats, survival, survminer
Suggests: kableExtra, knitr, testthat (≥ 3.1.2), utils
Published: 2025-10-09
DOI: 10.32614/CRAN.package.PERSUADE (may not be active yet)
Author: Bram Ramaekers ORCID iD [aut, cre, ths], Xavier Pouwels ORCID iD [ctb], Sabine Grimm ORCID iD [ths], Manuela Joore ORCID iD [ths]
Maintainer: Bram Ramaekers <bram.ramaekers at mumc.nl>
BugReports: https://github.com/Bram-R/PERSUADE/issues
License: GPL (≥ 3)
URL: https://github.com/Bram-R/PERSUADE
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: PERSUADE results

Documentation:

Reference manual: PERSUADE.html , PERSUADE.pdf
Vignettes: Introduction to PERSUADE (source, R code)

Downloads:

Package source: PERSUADE_0.1.2.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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