monolix2rx: Converts 'Monolix' Models to 'rxode2'

'Monolix' is a tool for running mixed effects model using 'saem'. This tool allows you to convert 'Monolix' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) using the form compatible with 'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>). If available, the 'rxode2' model will read in the 'Monolix' data and compare the simulation for the population model individual model and residual model to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'Monolix' and can convert the objects converted from 'monolix2rx' to a full 'nlmixr2' fit. While not required, you can get/install the 'lixoftConnectors' package in the 'Monolix' installation, as described at the following url <https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>. When 'lixoftConnectors' is available, 'Monolix' can be used to load its model library instead manually setting up text files (which only works with old versions of 'Monolix').

Version:	0.0.6
Imports:	Rcpp, checkmate, cli, dparser, withr, ggplot2, ggforce, stringi, crayon, lotri, magrittr, rxode2 (≥ 3.0.4)
LinkingTo:	dparser, rxode2, Rcpp
Suggests:	devtools, testthat (≥ 3.0.0), xgxr, vdiffr
Published:	2025-08-29
DOI:	10.32614/CRAN.package.monolix2rx
Author:	Matthew Fidler [aut, cre], Justin Wilkins [ctb]
Maintainer:	Matthew Fidler <matthew.fidler at gmail.com>
License:	MIT + file LICENSE
URL:	https://nlmixr2.github.io/monolix2rx/, https://github.com/nlmixr2/monolix2rx/
NeedsCompilation:	yes
Materials:	README, NEWS
CRAN checks:	monolix2rx results

Documentation:

Reference manual:

monolix2rx.html , monolix2rx.pdf

Downloads:

Package source:	monolix2rx_0.0.6.tar.gz
Windows binaries:	r-devel: monolix2rx_0.0.6.zip, r-release: monolix2rx_0.0.6.zip, r-oldrel: monolix2rx_0.0.6.zip
macOS binaries:	r-release (arm64): monolix2rx_0.0.6.tgz, r-oldrel (arm64): monolix2rx_0.0.6.tgz, r-release (x86_64): monolix2rx_0.0.6.tgz, r-oldrel (x86_64): monolix2rx_0.0.6.tgz
Old sources:	monolix2rx archive

Reverse dependencies:

Reverse imports:

babelmixr2

Linking:

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