Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.
| Version: | 0.2.1 | 
| Depends: | R (≥ 4.2.0) | 
| Imports: | ggplot2, stats, utils, mvtnorm, reshape, Rcpp, knitr | 
| LinkingTo: | Rcpp, RcppArmadillo | 
| Suggests: | testthat (≥ 2.1.0), rmarkdown, mrgsolve, gridExtra, reshape2, truncnorm, xtable | 
| Published: | 2025-09-27 | 
| DOI: | 10.32614/CRAN.package.tci | 
| Author: | Ryan Jarrett [aut, cre] | 
| Maintainer: | Ryan Jarrett <ryantjarrett at gmail.com> | 
| BugReports: | https://github.com/jarretrt/tci/issues | 
| License: | GPL-2 | 
| URL: | https://github.com/jarretrt/tci | 
| NeedsCompilation: | yes | 
| SystemRequirements: | C++17 | 
| Materials: | README | 
| CRAN checks: | tci results | 
| Reference manual: | tci.html , tci.pdf | 
| Vignettes: | Custom PK models and algorithms (source, R code) Introduction to tci package (source, R code) Population PK models (source, R code) | 
| Package source: | tci_0.2.1.tar.gz | 
| Windows binaries: | r-devel: tci_0.2.1.zip, r-release: tci_0.2.1.zip, r-oldrel: tci_0.2.1.zip | 
| macOS binaries: | r-release (arm64): tci_0.2.1.tgz, r-oldrel (arm64): tci_0.2.1.tgz, r-release (x86_64): tci_0.2.1.tgz, r-oldrel (x86_64): tci_0.2.1.tgz | 
| Old sources: | tci archive | 
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