Multiple platform build/check report for BioC 3.20 - CHECK results for maftools on merida1

Hostname	OS	Arch (*)	R version	Installed pkgs
nebbiolo2	Linux (Ubuntu 22.04.3 LTS)	x86_64	4.4.0 RC (2024-04-16 r86468) -- "Puppy Cup"	4679
palomino4	Windows Server 2022 Datacenter	x64	4.4.0 RC (2024-04-16 r86468 ucrt) -- "Puppy Cup"	4414
merida1	macOS 12.7.4 Monterey	x86_64	4.4.0 Patched (2024-04-24 r86482) -- "Puppy Cup"	4441
kjohnson1	macOS 13.6.6 Ventura	arm64	4.4.0 Patched (2024-04-24 r86482) -- "Puppy Cup"	4394
Click on any hostname to see more info about the system (e.g. compilers) () as reported by 'uname -p', except on Windows and Mac OS X*

CHECK results for maftools on merida1

To the developers/maintainers of the maftools package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/maftools.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results

Summary

Package: maftools

Version: 2.21.0

Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:maftools.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings maftools_2.21.0.tar.gz

StartedAt: 2024-06-10 05:38:06 -0400 (Mon, 10 Jun 2024)

EndedAt: 2024-06-10 05:43:14 -0400 (Mon, 10 Jun 2024)

EllapsedTime: 307.3 seconds

RetCode: 0

Status: OK

CheckDir: maftools.Rcheck

Warnings: 0

Command output

##############################################################################
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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:maftools.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings maftools_2.21.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.20-bioc/meat/maftools.Rcheck’
* using R version 4.4.0 Patched (2024-04-24 r86482)
* using platform: x86_64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 12.2.0
* running under: macOS Monterey 12.7.4
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘maftools/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘maftools’ version ‘2.21.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘maftools’ can be installed ... OK
* used C compiler: ‘Apple clang version 14.0.0 (clang-1400.0.29.202)’
* used SDK: ‘MacOSX11.3.sdk’
* checking installed package size ... NOTE
  installed size is  8.2Mb
  sub-directories of 1Mb or more:
    extdata   6.0Mb
    libs      1.0Mb
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
License stub is invalid DCF.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
Namespace in Imports field not imported from: ‘Rhtslib’
  All declared Imports should be used.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
.dnaCopy_plotter: no visible binding for global variable ‘contig’
.dnaCopy_plotter: no visible binding for global variable ‘Chromosome’
.dnaCopy_plotter: no visible global function definition for ‘par’
.dnaCopy_plotter: no visible global function definition for ‘abline’
.dnaCopy_plotter: no visible global function definition for ‘segments’
.dnaCopy_plotter: no visible global function definition for ‘axis’
.getdomains: no visible binding for global variable ‘HGNC’
.getdomains: no visible binding for global variable ‘refseq.ID’
.getdomains: no visible binding for global variable ‘protein.ID’
.getdomains: no visible global function definition for ‘.’
.getdomains: no visible binding for global variable ‘aa.length’
.mafSetKeys: no visible binding for global variable ‘Chromosome’
.mafSetKeys: no visible binding for global variable ‘Start_Position’
.mafSetKeys: no visible binding for global variable ‘End_Position’
add_legend: no visible global function definition for ‘par’
add_legend: no visible global function definition for ‘legend’
add_oncoprint: no visible global function definition for ‘unit’
add_oncoprint: no visible binding for global variable ‘bg’
add_oncoprint2: no visible global function definition for ‘unit’
annovarToMaf: no visible binding for global variable ‘Hugo_Symbol’
annovarToMaf: no visible binding for global variable ‘Gene.refGene’
annovarToMaf: no visible binding for global variable ‘Func.refGene’
annovarToMaf: no visible binding for global variable
  ‘ExonicFunc.refGene’
annovarToMaf: no visible binding for global variable ‘AAChange.refGene’
annovarToMaf: no visible binding for global variable ‘ref_alt_len’
annovarToMaf: no visible binding for global variable ‘Ref’
annovarToMaf: no visible binding for global variable ‘Alt’
annovarToMaf: no visible binding for global variable ‘ref_alt_diff’
annovarToMaf: no visible binding for global variable ‘Variant_Type’
annovarToMaf: no visible binding for global variable ‘ref_alt’
annovarToMaf: no visible binding for global variable ‘ens_id’
annovarToMaf: no visible binding for global variable ‘hgnc_symbol’
annovarToMaf: no visible binding for global variable ‘Entrez_Gene_Id’
annovarToMaf: no visible binding for global variable ‘Entrez’
binconf : bc: no visible global function definition for ‘qf’
binconf : bc: no visible global function definition for ‘qnorm’
bubble_plot: no visible global function definition for ‘layout’
bubble_plot: no visible global function definition for ‘symbols’
bubble_plot: no visible global function definition for ‘axis’
bubble_plot: no visible global function definition for ‘abline’
bubble_plot: no visible global function definition for ‘mtext’
bubble_plot: no visible global function definition for ‘text’
bubble_plot: no visible global function definition for ‘par’
cancerhotspots: no visible global function definition for ‘browseURL’
cancerhotspotsAggr : <anonymous>: no visible global function definition
  for ‘.’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘A’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘G’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘C’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘Ins’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘Del’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘t_depth’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘VAF’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘End_Position’
cancerhotspotsAggr : <anonymous>: no visible binding for global
  variable ‘Start_Position’
cancerhotspotsAggr: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
clinicalEnrichment : pairwise.fisher.test : compare.levels: no visible
  global function definition for ‘fisher.test’
clinicalEnrichment : pairwise.fisher.test: no visible global function
  definition for ‘pairwise.table’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Gene’
clinicalEnrichment: no visible binding for global variable
  ‘AlteredSamples’
clinicalEnrichment: no visible binding for global variable
  ‘Hugo_Symbol’
clinicalEnrichment: no visible binding for global variable
  ‘MutatedSamples’
clinicalEnrichment : <anonymous> : <anonymous>: no visible global
  function definition for ‘fisher.test’
clinicalEnrichment : <anonymous> : <anonymous>: no visible binding for
  global variable ‘Group’
clinicalEnrichment : <anonymous> : <anonymous>: no visible binding for
  global variable ‘Genotype’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Hugo_Symbol’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Analysis’
clinicalEnrichment : <anonymous>: no visible global function definition
  for ‘.’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Var1’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Var2’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘value’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘fdr’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘cf’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Genotype’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘N’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘n_mutated_Feature’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘N.x’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘N.y’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Feature_1’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘Feature_2’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘n_mutated_Feature1’
clinicalEnrichment : <anonymous>: no visible binding for global
  variable ‘n_mutated_Feature2’
clinicalEnrichment: no visible binding for global variable ‘Analysis’
clinicalEnrichment: no visible global function definition for ‘.’
clinicalEnrichment: no visible binding for global variable ‘Feature_1’
clinicalEnrichment: no visible binding for global variable ‘Feature_2’
clinicalEnrichment: no visible binding for global variable
  ‘n_mutated_Feature1’
clinicalEnrichment: no visible binding for global variable
  ‘n_mutated_Feature2’
clinicalEnrichment: no visible binding for global variable ‘fdr’
clinicalEnrichment: no visible binding for global variable ‘Group1’
clinicalEnrichment: no visible binding for global variable ‘Group2’
clinicalEnrichment: no visible binding for global variable
  ‘n_mutated_group1’
clinicalEnrichment: no visible binding for global variable
  ‘n_mutated_group2’
clinicalEnrichment: no visible binding for global variable ‘p_value’
clinicalEnrichment: no visible binding for global variable ‘OR’
clinicalEnrichment: no visible binding for global variable ‘OR_low’
clinicalEnrichment: no visible binding for global variable ‘OR_high’
clinicalEnrichment: no visible global function definition for
  ‘p.adjust’
clinicalEnrichment: no visible binding for global variable ‘cf’
cluster_prot: no visible binding for global variable ‘N’
cluster_prot: no visible binding for global variable ‘distance’
cluster_prot: no visible binding for global variable ‘startDist’
cluster_prot: no visible binding for global variable ‘endDist’
cluster_prot: no visible binding for global variable ‘fraction’
cluster_prot : <anonymous>: no visible binding for global variable
  ‘fraction’
coBarplot: no visible binding for global variable ‘Hugo_Symbol’
coBarplot: no visible binding for global variable ‘ID’
coBarplot: no visible global function definition for ‘.’
coBarplot: no visible binding for global variable ‘AlteredSamples’
coBarplot: no visible global function definition for ‘par’
coBarplot: no visible global function definition for ‘barplot’
coBarplot: no visible global function definition for ‘text’
coBarplot: no visible global function definition for ‘axis’
coBarplot: no visible global function definition for ‘mtext’
coBarplot: no visible global function definition for ‘title’
coBarplot: no visible global function definition for ‘legend’
coGisticChromPlot: no visible binding for global variable ‘Chromosome’
coGisticChromPlot: no visible binding for global variable ‘loc’
coGisticChromPlot: no visible binding for global variable
  ‘Start_Position’
coGisticChromPlot: no visible binding for global variable
  ‘End_Position’
coGisticChromPlot: no visible global function definition for ‘.’
coGisticChromPlot: no visible binding for global variable ‘qvalues’
coGisticChromPlot: no visible binding for global variable ‘Cytoband’
coGisticChromPlot: no visible binding for global variable
  ‘Variant_Classification’
coGisticChromPlot: no visible binding for global variable ‘value’
coGisticChromPlot: no visible global function definition for ‘layout’
coGisticChromPlot: no visible global function definition for ‘par’
coGisticChromPlot: no visible global function definition for ‘text’
coGisticChromPlot: no visible global function definition for ‘segments’
coGisticChromPlot: no visible global function definition for ‘axis’
coGisticChromPlot: no visible global function definition for ‘mtext’
coGisticChromPlot: no visible global function definition for ‘rect’
coGisticChromPlot: no visible global function definition for ‘lines’
coGisticChromPlot: no visible global function definition for ‘head’
coGisticChromPlot: no visible binding for global variable ‘gistic’
coGisticChromPlot: no visible binding for global variable
  ‘Start_Position_updated’
coGisticChromPlot: no visible binding for global variable
  ‘End_Position_updated’
coGisticChromPlot: no visible binding for global variable ‘ystart’
coGisticChromPlot: no visible global function definition for
  ‘complete.cases’
coGisticChromPlot: no visible global function definition for ‘rug’
coGisticChromPlot: no visible binding for global variable ‘Hugo_Symbol’
coGisticChromPlot: no visible binding for global variable ‘VC’
coGisticChromPlot: no visible binding for global variable ‘G_Score’
coGisticChromPlot: no visible binding for global variable
  ‘anno_Position’
coOncoplot: no visible binding for global variable ‘Hugo_Symbol’
coOncoplot: no visible global function definition for ‘.’
coOncoplot: no visible binding for global variable ‘MutatedSamples’
coOncoplot: no visible binding for global variable ‘MutatedSamples_m1’
coOncoplot: no visible binding for global variable ‘MutatedSamples_m2’
coOncoplot: no visible global function definition for ‘plot.new’
coOncoplot: no visible global function definition for ‘par’
coOncoplot: no visible global function definition for ‘image’
coOncoplot: no visible global function definition for ‘text’
coOncoplot: no visible global function definition for ‘legend’
createOncoMatrix: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
createOncoMatrix: no visible binding for global variable ‘Hugo_Symbol’
createOncoMatrix: no visible binding for global variable ‘Variant_Type’
createOncoMatrix: no visible binding for global variable
  ‘Variant_Classification’
createOncoMatrix: no visible binding for global variable
  ‘Variant_Classification_temp’
createOncoMatrix: no visible global function definition for ‘.’
dashboard: no visible binding for global variable ‘statFontSize’
dashboard: no visible binding for global variable ‘fs’
dashboard: no visible binding for global variable ‘pie’
dashboard: no visible global function definition for ‘par’
dashboard: no visible global function definition for ‘barplot’
dashboard: no visible global function definition for ‘abline’
dashboard: no visible global function definition for ‘axis’
dashboard: no visible global function definition for ‘title’
dashboard: no visible binding for global variable ‘value’
dashboard: no visible binding for global variable ‘variable’
dashboard: no visible global function definition for ‘text’
dashboard: no visible global function definition for ‘mtext’
dashboard: no visible binding for global variable ‘ID’
dashboard: no visible binding for global variable ‘Mean’
dashboard: no visible global function definition for ‘lines’
dashboard: no visible binding for global variable ‘Median’
dashboard: no visible binding for global variable ‘N’
dashboard: no visible global function definition for ‘.’
dashboard: no visible binding for global variable
  ‘Variant_Classification’
dashboard: no visible global function definition for ‘boxplot’
dashboard: no visible binding for global variable ‘boxStat’
dashboard: no visible binding for global variable ‘Hugo_Symbol’
dashboard: no visible binding for global variable ‘AlteredSamples’
detect_kataegis: no visible global function definition for
  ‘write.table’
detect_kataegis: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
detect_kataegis_chr: no visible binding for global variable ‘row_idx’
detect_kataegis_chr: no visible binding for global variable
  ‘Start_Position’
detect_kataegis_chr: no visible binding for global variable
  ‘Chromosome’
detect_kataegis_chr: no visible binding for global variable ‘Size’
detect_kataegis_chr: no visible binding for global variable
  ‘End_Position’
detect_kataegis_chr: no visible global function definition for ‘.’
detect_kataegis_chr: no visible binding for global variable ‘con.class’
detect_kataegis_chr: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
dirichletClusters: no visible binding for global variable ‘dp’
drugInteractions: no visible binding for global variable ‘Hugo_Symbol’
drugInteractions: no visible binding for global variable ‘Gene’
drugInteractions: no visible binding for global variable ‘N’
drugInteractions: no visible binding for global variable ‘category’
drugInteractions: no visible global function definition for ‘.’
drugInteractions: no visible binding for global variable ‘V1’
drugInteractions: no visible binding for global variable ‘label’
drugInteractions: no visible global function definition for ‘par’
drugInteractions: no visible global function definition for ‘pie’
drugInteractions: no visible global function definition for
  ‘heat.colors’
drugInteractions: no visible global function definition for ‘barplot’
drugInteractions: no visible global function definition for ‘text’
drugInteractions: no visible global function definition for ‘axis’
drugInteractions: no visible global function definition for ‘mtext’
drugInteractions: no visible global function definition for ‘title’
estimateSignatures: no visible global function definition for ‘png’
filterCopyNumber: no visible global function definition for ‘.’
filterCopyNumber: no visible binding for global variable ‘Hugo_Symbol’
filterCopyNumber: no visible binding for global variable ‘Chromosome’
filterCopyNumber: no visible binding for global variable
  ‘i.Start_Position’
filterCopyNumber: no visible binding for global variable
  ‘i.End_Position’
filterCopyNumber: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
filterCopyNumber: no visible binding for global variable ‘t_vaf’
filterCopyNumber: no visible binding for global variable
  ‘Start_Position’
filterCopyNumber: no visible binding for global variable ‘End_Position’
filterCopyNumber: no visible binding for global variable ‘Segment_Mean’
filterCopyNumber: no visible binding for global variable ‘CN’
filterMaf: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
filterMaf: no visible binding for global variable ‘Hugo_Symbol’
forestPlot: no visible binding for global variable ‘pval’
forestPlot: no visible binding for global variable ‘adjPval’
forestPlot: no visible binding for global variable ‘Cohort’
forestPlot: no visible binding for global variable ‘SampleSize’
forestPlot: no visible binding for global variable ‘pos’
forestPlot: no visible global function definition for ‘par’
forestPlot: no visible global function definition for ‘.’
forestPlot: no visible binding for global variable ‘or’
forestPlot: no visible binding for global variable ‘ci.up’
forestPlot: no visible binding for global variable ‘ci.low’
forestPlot: no visible binding for global variable ‘or_new’
forestPlot: no visible binding for global variable ‘upper’
forestPlot: no visible binding for global variable ‘lower’
forestPlot : <anonymous>: no visible global function definition for
  ‘points’
forestPlot : <anonymous>: no visible global function definition for
  ‘segments’
forestPlot: no visible global function definition for ‘abline’
forestPlot: no visible global function definition for ‘axis’
forestPlot: no visible global function definition for ‘mtext’
forestPlot: no visible global function definition for ‘title’
forestPlot: no visible global function definition for ‘text’
genesToBarcodes: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
genesToBarcodes : <anonymous>: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
genotypeMatrix: no visible binding for global variable ‘id’
genotypeMatrix: no visible binding for global variable ‘Chromosome’
genotypeMatrix: no visible binding for global variable ‘Start_Position’
genotypeMatrix: no visible binding for global variable ‘t_vaf’
get_anno_cols: no visible global function definition for
  ‘colorRampPalette’
get_col_df: no visible binding for global variable ‘Hugo_Symbol’
get_col_df: no visible binding for global variable ‘Var1’
get_col_df: no visible binding for global variable ‘Freq’
get_col_df: no visible global function definition for ‘.’
get_col_df: no visible binding for global variable ‘Gene’
get_lp_data: no visible binding for global variable ‘Hugo_Symbol’
get_lp_data: no visible global function definition for ‘.’
get_lp_data: no visible binding for global variable ‘Variant_Type’
get_lp_data: no visible binding for global variable
  ‘Variant_Classification’
get_lp_data: no visible binding for global variable ‘AAChange’
get_lp_data: no visible binding for global variable ‘HGNC’
get_lp_data: no visible binding for global variable ‘refseq.ID’
get_lp_data: no visible binding for global variable ‘protein.ID’
get_lp_data: no visible binding for global variable ‘aa.length’
get_lp_data: no visible binding for global variable ‘domain_lenght’
get_lp_data: no visible binding for global variable ‘End’
get_lp_data: no visible binding for global variable ‘Start’
get_lp_data: no visible binding for global variable ‘ID’
get_lp_data: no visible binding for global variable ‘MutatedSamples’
get_lp_data: no visible binding for global variable ‘conv’
get_lp_data: no visible binding for global variable ‘count2’
get_lp_data: no visible binding for global variable ‘count’
get_lp_data: no visible binding for global variable ‘posRounded’
get_lp_data: no visible binding for global variable ‘lab’
get_lp_data: no visible binding for global variable ‘Label’
get_pw_summary: no visible binding for global variable ‘Pathway’
get_pw_summary: no visible binding for global variable
  ‘fraction_affected’
get_pw_summary: no visible binding for global variable
  ‘n_affected_genes’
get_pw_summary: no visible binding for global variable ‘N’
get_pw_summary: no visible binding for global variable ‘ID’
get_pw_summary: no visible binding for global variable
  ‘Fraction_mutated_samples’
get_pw_summary: no visible binding for global variable
  ‘Mutated_samples’
get_pw_summary: no visible global function definition for ‘.’
get_threshold : <anonymous>: no visible global function definition for
  ‘dbinom’
gisticBubblePlot: no visible binding for global variable ‘qvalues’
gisticBubblePlot: no visible binding for global variable ‘Chromosome’
gisticBubblePlot: no visible binding for global variable ‘loc’
gisticBubblePlot: no visible binding for global variable
  ‘Start_Position’
gisticBubblePlot: no visible binding for global variable ‘End_Position’
gisticBubblePlot: no visible global function definition for ‘.’
gisticBubblePlot: no visible binding for global variable ‘Cytoband’
gisticBubblePlot: no visible binding for global variable
  ‘Variant_Classification’
gisticBubblePlot: no visible binding for global variable ‘nGenes’
gisticBubblePlot: no visible binding for global variable ‘log_q’
gisticBubblePlot: no visible global function definition for ‘par’
gisticChromPlot: no visible binding for global variable ‘qvalues’
gisticChromPlot: no visible binding for global variable ‘Chromosome’
gisticChromPlot: no visible binding for global variable ‘loc’
gisticChromPlot: no visible binding for global variable
  ‘Start_Position’
gisticChromPlot: no visible binding for global variable ‘End_Position’
gisticChromPlot: no visible global function definition for ‘.’
gisticChromPlot: no visible binding for global variable ‘Cytoband’
gisticChromPlot: no visible binding for global variable
  ‘Variant_Classification’
gisticChromPlot: no visible binding for global variable ‘amp’
gisticChromPlot: no visible global function definition for ‘layout’
gisticChromPlot: no visible global function definition for ‘par’
gisticChromPlot: no visible global function definition for ‘abline’
gisticChromPlot: no visible global function definition for ‘axis’
gisticChromPlot: no visible global function definition for ‘mtext’
gisticChromPlot: no visible global function definition for ‘segments’
gisticChromPlot: no visible global function definition for ‘rect’
gisticChromPlot: no visible global function definition for ‘text’
gisticChromPlot: no visible binding for global variable
  ‘Start_Position_updated’
gisticChromPlot: no visible binding for global variable
  ‘End_Position_updated’
gisticChromPlot: no visible global function definition for
  ‘complete.cases’
gisticChromPlot: no visible binding for global variable ‘Hugo_Symbol’
gisticChromPlot: no visible binding for global variable ‘G_Score’
gisticChromPlot: no visible binding for global variable ‘fdr’
gisticMap: no visible binding for global variable ‘Cytoband’
gisticMap: no visible binding for global variable
  ‘Variant_Classification’
gisticOncoPlot: no visible global function definition for ‘par’
gisticOncoPlot: no visible global function definition for ‘image’
gisticOncoPlot: no visible global function definition for ‘abline’
gisticOncoPlot: no visible global function definition for ‘mtext’
gisticOncoPlot: no visible global function definition for ‘text’
gisticOncoPlot: no visible global function definition for ‘legend’
gtMarkers: no visible global function definition for ‘download.file’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘consequence_type’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘gene_affected’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘assembly_version’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘chromosome’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘chromosome_start’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘chromosome_end’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Variant_Classification’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Variant_Type’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘reference_genome_allele’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘mutated_from_allele’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘mutated_to_allele’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘icgc_sample_id’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘verification_status’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘sequencing_strategy’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘verification_platform’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘ens_id’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Hugo_Symbol’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘hgnc_symbol’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Entrez_Gene_Id’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Entrez’
icgcSimpleMutationToMAF: no visible global function definition for
  ‘write.table’
icgcSimpleMutationToMAF: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
inferHeterogeneity: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
inferHeterogeneity: no visible binding for global variable ‘t_vaf’
inferHeterogeneity: no visible binding for global variable
  ‘t_alt_count’
inferHeterogeneity: no visible binding for global variable
  ‘t_ref_count’
inferHeterogeneity: no visible binding for global variable ‘Chromosome’
inferHeterogeneity: no visible binding for global variable
  ‘Start_Position’
inferHeterogeneity: no visible binding for global variable
  ‘End_Position’
inferHeterogeneity: no visible binding for global variable ‘Sample’
inferHeterogeneity: no visible global function definition for ‘.’
inferHeterogeneity: no visible binding for global variable
  ‘Hugo_Symbol’
inferHeterogeneity: no visible global function definition for ‘median’
intersectMAF: no visible binding for global variable ‘Chromosome’
intersectMAF: no visible binding for global variable ‘Start_Position’
intersectMAF: no visible binding for global variable ‘End_Position’
intersectMAF: no visible global function definition for ‘.’
intersectMAF: no visible binding for global variable ‘Reference_Allele’
intersectMAF: no visible binding for global variable
  ‘Tumor_Seq_Allele2’
intersectMAF: no visible binding for global variable ‘variant_ID’
intersectMAF: no visible binding for global variable ‘maf_slot’
label_pos: no visible binding for global variable ‘labThis’
label_pos: no visible binding for global variable ‘pos2’
label_pos: no visible binding for global variable ‘count2’
label_pos: no visible binding for global variable ‘conv’
lollipopPlot: no visible binding for global variable ‘domain_lenght’
lollipopPlot: no visible binding for global variable ‘End’
lollipopPlot: no visible binding for global variable ‘Start’
lollipopPlot: no visible binding for global variable ‘Hugo_Symbol’
lollipopPlot: no visible global function definition for ‘.’
lollipopPlot: no visible binding for global variable ‘Variant_Type’
lollipopPlot: no visible binding for global variable
  ‘Variant_Classification’
lollipopPlot: no visible binding for global variable ‘AAChange_’
lollipopPlot: no visible binding for global variable ‘ID’
lollipopPlot: no visible binding for global variable ‘MutatedSamples’
lollipopPlot: no visible binding for global variable ‘conv’
lollipopPlot: no visible binding for global variable ‘count2’
lollipopPlot: no visible binding for global variable ‘count’
lollipopPlot: no visible binding for global variable ‘posRounded’
lollipopPlot: no visible binding for global variable ‘lab’
lollipopPlot: no visible binding for global variable ‘labThis’
lollipopPlot: no visible binding for global variable ‘pos2’
lollipopPlot: no visible binding for global variable ‘Label’
lollipopPlot: no visible global function definition for ‘par’
lollipopPlot: no visible global function definition for ‘rect’
lollipopPlot: no visible global function definition for ‘axis’
lollipopPlot: no visible global function definition for ‘segments’
lollipopPlot: no visible global function definition for ‘points’
lollipopPlot: no visible binding for global variable ‘domainCol’
lollipopPlot: no visible global function definition for ‘title’
lollipopPlot: no visible binding for global variable ‘refseq.ID’
lollipopPlot: no visible global function definition for ‘text’
lollipopPlot: no visible global function definition for ‘legend’
lollipopPlot2: no visible binding for global variable ‘Label’
lollipopPlot2: no visible binding for global variable
  ‘Variant_Classification’
lollipopPlot2: no visible global function definition for ‘par’
lollipopPlot2: no visible global function definition for ‘rect’
lollipopPlot2: no visible global function definition for ‘axis’
lollipopPlot2: no visible global function definition for ‘segments’
lollipopPlot2: no visible binding for global variable ‘pos2’
lollipopPlot2: no visible binding for global variable ‘count2’
lollipopPlot2: no visible global function definition for ‘points’
lollipopPlot2: no visible binding for global variable ‘domainCol’
lollipopPlot2: no visible binding for global variable ‘Start’
lollipopPlot2: no visible binding for global variable ‘End’
lollipopPlot2: no visible global function definition for ‘.’
lollipopPlot2: no visible global function definition for ‘text’
lollipopPlot2: no visible global function definition for ‘mtext’
lollipopPlot2: no visible binding for global variable ‘refseq.ID’
lollipopPlot2: no visible binding for global variable ‘conv’
lollipopPlot2: no visible global function definition for ‘legend’
mafCompare: no visible global function definition for ‘.’
mafCompare: no visible binding for global variable ‘Pathway’
mafCompare: no visible binding for global variable ‘Mutated_samples’
mafCompare: no visible binding for global variable ‘AlteredSamples’
mafCompare: no visible binding for global variable ‘Hugo_Symbol’
mafCompare: no visible binding for global variable ‘MutatedSamples’
mafCompare : <anonymous>: no visible global function definition for
  ‘fisher.test’
mafCompare: no visible binding for global variable ‘pval’
mafCompare: no visible binding for global variable ‘adjPval’
mafCompare: no visible global function definition for ‘p.adjust’
mafSurvGroup: no visible binding for global variable ‘Time’
mafSurvGroup: no visible global function definition for ‘.’
mafSurvGroup: no visible global function definition for ‘median’
mafSurvGroup: no visible binding for global variable ‘Group’
mafSurvGroup: no visible global function definition for ‘pchisq’
mafSurvGroup: no visible global function definition for ‘par’
mafSurvGroup: no visible global function definition for ‘abline’
mafSurvGroup: no visible global function definition for ‘points’
mafSurvGroup: no visible binding for global variable ‘survProb’
mafSurvGroup: no visible global function definition for ‘lines’
mafSurvGroup: no visible global function definition for ‘axis’
mafSurvGroup: no visible global function definition for ‘mtext’
mafSurvGroup: no visible global function definition for ‘legend’
mafSurvGroup: no visible global function definition for ‘title’
mafSurvival: no visible binding for global variable ‘Time’
mafSurvival: no visible global function definition for ‘.’
mafSurvival: no visible global function definition for ‘median’
mafSurvival: no visible binding for global variable ‘Group’
mafSurvival: no visible global function definition for ‘pchisq’
mafSurvival: no visible global function definition for ‘par’
mafSurvival: no visible global function definition for ‘abline’
mafSurvival: no visible global function definition for ‘points’
mafSurvival: no visible binding for global variable ‘survProb’
mafSurvival: no visible global function definition for ‘lines’
mafSurvival: no visible global function definition for ‘axis’
mafSurvival: no visible global function definition for ‘mtext’
mafSurvival: no visible global function definition for ‘legend’
mafSurvival: no visible global function definition for ‘title’
mafbarplot: no visible binding for global variable ‘ID’
mafbarplot: no visible global function definition for ‘.’
mafbarplot: no visible binding for global variable ‘Hugo_Symbol’
mafbarplot: no visible binding for global variable ‘AlteredSamples’
mafbarplot: no visible global function definition for ‘par’
mafbarplot: no visible global function definition for ‘barplot’
mafbarplot: no visible global function definition for ‘axis’
mafbarplot: no visible global function definition for ‘text’
mafbarplot: no visible global function definition for ‘abline’
mafbarplot: no visible global function definition for ‘mtext’
mafbarplot: no visible global function definition for ‘legend’
mapMutsToSegs: no visible binding for global variable ‘Sample’
mapMutsToSegs: no visible binding for global variable ‘Chromosome’
mapMutsToSegs: no visible binding for global variable ‘Start_Position’
mapMutsToSegs: no visible binding for global variable ‘End_Position’
mapMutsToSegs: no visible binding for global variable ‘Variant_Type’
mapMutsToSegs: no visible global function definition for ‘.’
mapMutsToSegs: no visible binding for global variable ‘Hugo_Symbol’
mapMutsToSegs: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
mapMutsToSegs: no visible binding for global variable
  ‘i.Start_Position’
mapMutsToSegs: no visible binding for global variable ‘i.End_Position’
mapMutsToSegs: no visible binding for global variable ‘Segment_Mean’
mapMutsToSegs: no visible binding for global variable
  ‘Start_Position_updated’
mapMutsToSegs: no visible binding for global variable
  ‘End_Position_updated’
mapMutsToSegs: no visible binding for global variable ‘CN’
math.score: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
math.score: no visible binding for global variable ‘t_ref_count’
math.score: no visible binding for global variable ‘t_alt_count’
math.score: no visible binding for global variable ‘t_vaf’
math.score: no visible global function definition for ‘.’
math.score: no visible binding for global variable ‘Hugo_Symbol’
math.score : <anonymous>: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
math.score : <anonymous>: no visible global function definition for
  ‘median’
mutCountMatrix: no visible binding for global variable
  ‘Variant_Classification’
mutCountMatrix: no visible global function definition for ‘.’
mutCountMatrix: no visible binding for global variable ‘Hugo_Symbol’
mutCountMatrix: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
mutCountMatrix: no visible binding for global variable ‘tot’
oncodrive: no visible global function definition for ‘read.csv’
oncodrive: no visible global function definition for ‘sd’
oncodrive: no visible binding for global variable ‘Hugo_Symbol’
oncodrive: no visible global function definition for ‘pnorm’
oncodrive: no visible global function definition for ‘p.adjust’
oncodrive: no visible binding for global variable
  ‘fract_muts_in_clusters’
oncodrive: no visible binding for global variable ‘muts_in_clusters’
oncodrive: no visible binding for global variable ‘total’
oncodrive: no visible global function definition for ‘glm’
oncodrive: no visible global function definition for ‘poisson’
oncodrive : <anonymous>: no visible global function definition for
  ‘poisson.test’
oncodrive: no visible binding for global variable ‘poissonFdr’
oncodrive: no visible global function definition for ‘.’
oncodrive: no visible binding for global variable ‘tFdr’
oncodrive: no visible binding for global variable ‘fdr’
oncoplot: no visible binding for global variable ‘Gene’
oncoplot: no visible global function definition for ‘.’
oncoplot: no visible binding for global variable ‘Pathway’
oncoplot: no visible binding for global variable ‘AlteredSamples’
oncoplot: no visible binding for global variable ‘Hugo_Symbol’
oncoplot: no visible binding for global variable ‘MutatedSamples’
oncoplot: no visible binding for global variable ‘fractMutated’
oncoplot: no visible binding for global variable ‘mutload’
oncoplot: no visible binding for global variable ‘Tumor_Sample_Barcode’
oncoplot: no visible binding for global variable ‘total’
oncoplot: no visible binding for global variable
  ‘Variant_Classification_temp’
oncoplot: no visible binding for global variable
  ‘Variant_Classification’
oncoplot: no visible binding for global variable ‘value’
oncoplot: no visible binding for global variable ‘CNV_total’
oncoplot: no visible binding for global variable ‘Amp’
oncoplot: no visible binding for global variable ‘Del’
oncoplot: no visible binding for global variable ‘max_alt’
oncoplot: no visible binding for global variable ‘n’
oncoplot : <anonymous>: no visible binding for global variable
  ‘pct_alt’
oncoplot: no visible global function definition for ‘par’
oncoplot: no visible global function definition for ‘axis’
oncoplot: no visible global function definition for ‘rect’
oncoplot: no visible global function definition for ‘mtext’
oncoplot: no visible global function definition for ‘abline’
oncoplot: no visible global function definition for ‘title’
oncoplot: no visible global function definition for ‘image’
oncoplot: no visible global function definition for ‘write.table’
oncoplot: no visible binding for global variable ‘row_id’
oncoplot : <anonymous>: no visible global function definition for
  ‘rect’
oncoplot: no visible binding for global variable ‘temp_af’
oncoplot : <anonymous> : <anonymous>: no visible global function
  definition for ‘points’
oncoplot: no visible global function definition for ‘box’
oncoplot: no visible global function definition for ‘text’
oncoplot: no visible global function definition for ‘plot.new’
oncoplot: no visible global function definition for ‘legend’
parse_prot: no visible global function definition for ‘.’
parse_prot: no visible binding for global variable ‘Hugo_Symbol’
parse_prot: no visible binding for global variable
  ‘Variant_Classification’
parse_prot: no visible binding for global variable ‘AAChange’
parse_prot: no visible binding for global variable ‘conv’
parse_prot: no visible binding for global variable ‘aa.length’
parse_prot: no visible binding for global variable ‘total’
parse_prot: no visible global function definition for ‘txtProgressBar’
parse_prot: no visible binding for global variable ‘th’
parse_prot: no visible global function definition for
  ‘setTxtProgressBar’
pathway_load: no visible binding for global variable ‘Gene’
pathway_load: no visible global function definition for ‘.’
pathway_load: no visible binding for global variable ‘Pathway’
pathway_load: no visible binding for global variable
  ‘fraction_affected’
pathway_load: no visible binding for global variable ‘n_affected_genes’
pathway_load: no visible binding for global variable ‘N’
pathway_load: no visible binding for global variable ‘ID’
pathway_load: no visible binding for global variable
  ‘Fraction_mutated_samples’
pathway_load: no visible binding for global variable ‘Mutated_samples’
pathways: no visible binding for global variable ‘n_affected_genes’
pathways: no visible binding for global variable
  ‘Fraction_mutated_samples’
pathways : draw_rect: no visible global function definition for ‘rect’
pathways : draw_text: no visible global function definition for ‘text’
pathways : draw_text_sub: no visible global function definition for
  ‘text’
pathways: no visible binding for global variable ‘ID’
pathways: no visible global function definition for ‘layout’
pathways: no visible global function definition for ‘par’
pathways: no visible global function definition for ‘text’
pathways: no visible global function definition for ‘title’
pathways: no visible global function definition for ‘rect’
pathways: no visible global function definition for ‘axis’
pfamDomains: no visible binding for global variable ‘Variant_Type’
pfamDomains: no visible global function definition for ‘.’
pfamDomains: no visible binding for global variable ‘Hugo_Symbol’
pfamDomains: no visible binding for global variable
  ‘Variant_Classification’
pfamDomains: no visible binding for global variable ‘AAChange’
pfamDomains: no visible binding for global variable ‘conv’
pfamDomains: no visible binding for global variable ‘total’
pfamDomains: no visible binding for global variable ‘N’
pfamDomains: no visible binding for global variable ‘fraction’
pfamDomains: no visible binding for global variable ‘HGNC’
pfamDomains: no visible binding for global variable ‘Start’
pfamDomains: no visible binding for global variable ‘End’
pfamDomains: no visible binding for global variable ‘Label’
pfamDomains: no visible binding for global variable ‘pfam’
pfamDomains: no visible binding for global variable ‘Description’
pfamDomains: no visible binding for global variable ‘idx’
pfamDomains: no visible binding for global variable ‘DomainLabel’
pfamDomains: no visible binding for global variable ‘nMut’
pfamDomains: no visible binding for global variable ‘nGenes’
pfamDomains: no visible global function definition for ‘complete.cases’
pfamDomains: no visible binding for global variable ‘nMuts’
pfamDomains: no visible global function definition for ‘write.table’
pfamDomains: no visible global function definition for ‘par’
pfamDomains: no visible global function definition for ‘mtext’
plotApobecDiff: no visible binding for global variable
  ‘APOBEC_Enriched’
plotApobecDiff: no visible binding for global variable
  ‘fraction_APOBEC_mutations’
plotApobecDiff: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
plotApobecDiff: no visible binding for global variable ‘ID’
plotApobecDiff: no visible global function definition for ‘.’
plotApobecDiff: no visible binding for global variable ‘Mean’
plotApobecDiff: no visible binding for global variable ‘Median’
plotApobecDiff: no visible binding for global variable ‘Cohort’
plotApobecDiff: no visible binding for global variable ‘pval’
plotApobecDiff: no visible binding for global variable ‘Hugo_Symbol’
plotApobecDiff: no visible binding for global variable ‘MutatedSamples’
plotApobecDiff: no visible binding for global variable ‘SampleSize’
plotApobecDiff: no visible binding for global variable ‘nonApobec’
plotApobecDiff: no visible binding for global variable ‘V1’
plotApobecDiff: no visible binding for global variable ‘title’
plotApobecDiff: no visible binding for global variable ‘variable’
plotApobecDiff: no visible binding for global variable ‘value’
plotApobecDiff: no visible global function definition for ‘par’
plotApobecDiff: no visible binding for global variable ‘n_mutations’
plotApobecDiff: no visible global function definition for ‘boxplot’
plotApobecDiff: no visible global function definition for ‘title’
plotApobecDiff: no visible global function definition for ‘axis’
plotApobecDiff: no visible global function definition for ‘na.omit’
plotApobecDiff: no visible binding for global variable ‘N’
plotApobecDiff: no visible global function definition for ‘mtext’
plotApobecDiff: no visible global function definition for ‘wilcox.test’
plotApobecDiff: no visible global function definition for ‘text’
plotApobecDiff: no visible global function definition for ‘segments’
plotApobecDiff: no visible global function definition for ‘pie’
plotApobecDiff: no visible global function definition for ‘symbols’
plotApobecDiff: no visible global function definition for ‘barplot’
plotCBS: no visible binding for global variable ‘Sample’
plotCBS: no visible binding for global variable ‘Chromosome’
plotCBS: no visible binding for global variable ‘Start_Position’
plotCBS: no visible global function definition for ‘par’
plotCBS: no visible global function definition for ‘axis’
plotCBS: no visible global function definition for ‘abline’
plotCBS: no visible global function definition for ‘rect’
plotCBS: no visible global function definition for ‘title’
plotCBS: no visible global function definition for ‘mtext’
plotCBSchr: no visible binding for global variable ‘Sample’
plotCBSchr: no visible binding for global variable ‘Chromosome’
plotCBSsegments: no visible binding for global variable ‘Chromosome’
plotCBSsegments: no visible binding for global variable
  ‘Start_Position’
plotCBSsegments: no visible binding for global variable ‘End_Position’
plotCBSsegments: no visible binding for global variable ‘Sample’
plotCBSsegments: no visible global function definition for
  ‘write.table’
plotCBSsegments: no visible global function definition for ‘.’
plotCBSsegments: no visible binding for global variable ‘Hugo_Symbol’
plotCBSsegments: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
plotCBSsegments: no visible binding for global variable ‘Segment_Start’
plotCBSsegments: no visible binding for global variable ‘Segment_End’
plotCBSsegments: no visible binding for global variable ‘Segment_Mean’
plotCBSsegments: no visible binding for global variable ‘CN’
plotCBSsegments: no visible global function definition for ‘text’
plotCBSsegments: no visible global function definition for ‘segments’
plotClusters: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
plotClusters: no visible global function definition for ‘par’
plotClusters: no visible global function definition for ‘boxplot’
plotClusters: no visible binding for global variable ‘t_vaf’
plotClusters: no visible global function definition for ‘density’
plotClusters: no visible global function definition for ‘lines’
plotClusters: no visible global function definition for ‘abline’
plotClusters: no visible global function definition for ‘axis’
plotClusters: no visible global function definition for ‘points’
plotClusters: no visible global function definition for ‘title’
plotClusters: no visible binding for global variable ‘MATH’
plotClusters: no visible global function definition for ‘segments’
plotClusters: no visible global function definition for ‘text’
plotClusters: no visible binding for global variable ‘Hugo_Symbol’
plotClusters: no visible global function definition for ‘legend’
plotClusters: no visible global function definition for ‘mtext’
plotCophenetic: no visible global function definition for ‘par’
plotCophenetic: no visible global function definition for ‘axis’
plotCophenetic: no visible global function definition for ‘lines’
plotCophenetic: no visible global function definition for ‘points’
plotCophenetic: no visible global function definition for ‘segments’
plotCophenetic: no visible binding for global variable ‘cophenetic’
plotCophenetic: no visible global function definition for ‘title’
plotEnrichmentResults: no visible binding for global variable ‘P_value’
plotEnrichmentResults: no visible binding for global variable ‘OR’
plotEnrichmentResults: no visible binding for global variable ‘Group1’
plotEnrichmentResults : <anonymous>: no visible binding for global
  variable ‘g1_muts’
plotEnrichmentResults : <anonymous>: no visible binding for global
  variable ‘g1_tot’
plotEnrichmentResults : <anonymous>: no visible binding for global
  variable ‘g2_muts’
plotEnrichmentResults : <anonymous>: no visible binding for global
  variable ‘g2_tot’
plotEnrichmentResults: no visible binding for global variable
  ‘g1_title’
plotEnrichmentResults: no visible binding for global variable ‘g1_muts’
plotEnrichmentResults: no visible binding for global variable ‘g1_tot’
plotEnrichmentResults: no visible binding for global variable
  ‘g2_title’
plotEnrichmentResults: no visible binding for global variable ‘g2_muts’
plotEnrichmentResults: no visible binding for global variable ‘g2_tot’
plotEnrichmentResults : add_legend: no visible global function
  definition for ‘par’
plotEnrichmentResults : add_legend: no visible global function
  definition for ‘legend’
plotEnrichmentResults: no visible global function definition for ‘par’
plotEnrichmentResults: no visible global function definition for
  ‘barplot’
plotEnrichmentResults: no visible global function definition for ‘axis’
plotEnrichmentResults: no visible global function definition for
  ‘segments’
plotEnrichmentResults: no visible global function definition for ‘text’
plotEnrichmentResults: no visible global function definition for
  ‘legend’
plotEnrichmentResults: no visible global function definition for
  ‘title’
plotMosdepth : <anonymous>: no visible binding for global variable
  ‘chr’
plotMosdepth : <anonymous>: no visible binding for global variable
  ‘Chromosome’
plotMosdepth: no visible binding for global variable ‘Chromosome’
plotMosdepth: no visible binding for global variable ‘Start_Position’
plotMosdepth: no visible binding for global variable ‘End_Position’
plotMosdepth: no visible global function definition for ‘.’
plotMosdepth: no visible binding for global variable ‘logR’
plotMosdepth: no visible binding for global variable ‘doc_t’
plotMosdepth: no visible binding for global variable ‘doc_n’
plotMosdepth: no visible global function definition for ‘par’
plotMosdepth : <anonymous>: no visible global function definition for
  ‘points’
plotMosdepth : <anonymous>: no visible global function definition for
  ‘rect’
plotMosdepth: no visible global function definition for ‘abline’
plotMosdepth: no visible global function definition for ‘axis’
plotMosdepth: no visible global function definition for ‘mtext’
plotMosdepth: no visible global function definition for ‘title’
plotMosdepth_t: no visible binding for global variable ‘chr’
plotMosdepth_t: no visible binding for global variable ‘start’
plotMosdepth_t: no visible global function definition for ‘median’
plotMosdepth_t: no visible binding for global variable ‘doc’
plotMosdepth_t: no visible binding for global variable ‘End_Position’
plotMosdepth_t: no visible global function definition for ‘.’
plotMosdepth_t: no visible binding for global variable ‘Chromosome’
plotMosdepth_t: no visible binding for global variable ‘doc_norm’
plotMosdepth_t: no visible binding for global variable ‘Start_Position’
plotMosdepth_t: no visible global function definition for ‘par’
plotMosdepth_t : <anonymous>: no visible global function definition for
  ‘points’
plotMosdepth_t : <anonymous>: no visible global function definition for
  ‘rect’
plotMosdepth_t : <anonymous>: no visible binding for global variable
  ‘Start_Position_updated’
plotMosdepth_t : <anonymous>: no visible binding for global variable
  ‘End_Position_updated’
plotMosdepth_t: no visible global function definition for ‘abline’
plotMosdepth_t: no visible global function definition for ‘axis’
plotMosdepth_t: no visible global function definition for ‘title’
plotOncodrive: no visible binding for global variable ‘log_fdr’
plotOncodrive: no visible binding for global variable ‘fdr’
plotOncodrive: no visible global function definition for ‘par’
plotOncodrive: no visible binding for global variable ‘significant’
plotOncodrive: no visible global function definition for ‘mtext’
plotPathways: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
plotPathways: no visible global function definition for ‘par’
plotPathways: no visible global function definition for ‘image’
plotPathways: no visible global function definition for ‘abline’
plotPathways: no visible global function definition for ‘mtext’
plotPathways: no visible global function definition for ‘text’
plotProtein: no visible binding for global variable ‘HGNC’
plotProtein: no visible binding for global variable ‘refseq.ID’
plotProtein: no visible binding for global variable ‘protein.ID’
plotProtein: no visible global function definition for ‘.’
plotProtein: no visible binding for global variable ‘aa.length’
plotProtein: no visible binding for global variable ‘domain_lenght’
plotProtein: no visible binding for global variable ‘End’
plotProtein: no visible binding for global variable ‘Start’
plotProtein: no visible binding for global variable ‘Label’
plotProtein: no visible global function definition for ‘par’
plotProtein: no visible global function definition for ‘rect’
plotProtein: no visible binding for global variable ‘domainCol’
plotProtein: no visible global function definition for ‘text’
plotProtein: no visible global function definition for ‘title’
plotProtein: no visible global function definition for ‘legend’
plotSignatures: no visible global function definition for ‘par’
plotSignatures: no visible global function definition for ‘barplot’
plotSignatures: no visible global function definition for ‘axis’
plotSignatures: no visible global function definition for ‘mtext’
plotSignatures: no visible global function definition for ‘plot.new’
plotSignatures: no visible global function definition for ‘legend’
plotSignatures: no visible global function definition for ‘title’
plotSignatures: no visible global function definition for ‘rect’
plotSignatures: no visible global function definition for ‘text’
plotTiTv: no visible binding for global variable ‘value’
plotTiTv: no visible global function definition for ‘.’
plotTiTv: no visible binding for global variable ‘variable’
plotTiTv: no visible binding for global variable ‘V1’
plotTiTv: no visible global function definition for ‘par’
plotTiTv: no visible global function definition for ‘barplot’
plotTiTv: no visible global function definition for ‘axis’
plotTiTv: no visible global function definition for ‘mtext’
plotTiTv: no visible global function definition for ‘boxplot’
plotTiTv: no visible global function definition for ‘abline’
plotVaf: no visible binding for global variable ‘Hugo_Symbol’
plotVaf: no visible binding for global variable ‘t_vaf’
plotVaf: no visible binding for global variable ‘t_alt_count’
plotVaf: no visible binding for global variable ‘t_ref_count’
plotVaf: no visible global function definition for ‘.’
plotVaf: no visible binding for global variable ‘value’
plotVaf: no visible global function definition for ‘median’
plotVaf: no visible binding for global variable ‘V1’
plotVaf: no visible global function definition for ‘par’
plotVaf: no visible global function definition for ‘boxplot’
plotVaf: no visible global function definition for ‘axis’
plotVaf: no visible global function definition for ‘abline’
plotVaf: no visible global function definition for ‘stripchart’
plotmafSummary: no visible binding for global variable ‘statFontSize’
plotmafSummary: no visible global function definition for ‘par’
plotmafSummary: no visible global function definition for ‘barplot’
plotmafSummary: no visible global function definition for ‘axis’
plotmafSummary: no visible global function definition for ‘title’
plotmafSummary: no visible binding for global variable ‘Mean’
plotmafSummary: no visible binding for global variable ‘Median’
plotmafSummary: no visible global function definition for ‘lines’
plotmafSummary: no visible binding for global variable ‘N’
plotmafSummary: no visible global function definition for ‘.’
plotmafSummary: no visible binding for global variable
  ‘Variant_Classification’
plotmafSummary: no visible global function definition for ‘boxplot’
plotmafSummary: no visible binding for global variable ‘boxStat’
plotmafSummary: no visible global function definition for ‘plot.new’
plotmafSummary: no visible global function definition for ‘legend’
prepAscat : <anonymous>: no visible binding for global variable ‘loci’
prepAscat : <anonymous>: no visible binding for global variable
  ‘tot_depth’
prepAscat : <anonymous>: no visible global function definition for ‘.’
prepAscat : <anonymous>: no visible binding for global variable ‘A’
prepAscat : <anonymous>: no visible binding for global variable ‘G’
prepAscat : <anonymous>: no visible binding for global variable ‘C’
prepAscat : <anonymous>: no visible binding for global variable ‘baf’
prepAscat : <anonymous>: no visible global function definition for
  ‘runif’
prepAscat_t : <anonymous>: no visible binding for global variable
  ‘loci’
prepAscat_t : <anonymous>: no visible binding for global variable
  ‘tot_depth’
prepAscat_t : <anonymous>: no visible global function definition for
  ‘.’
prepAscat_t : <anonymous>: no visible binding for global variable ‘A’
prepAscat_t : <anonymous>: no visible binding for global variable ‘G’
prepAscat_t : <anonymous>: no visible binding for global variable ‘C’
prepAscat_t : <anonymous>: no visible binding for global variable ‘baf’
prepAscat_t : <anonymous>: no visible global function definition for
  ‘runif’
prepAscat_t: no visible global function definition for ‘median’
prepareMutSig: no visible binding for global variable
  ‘Variant_Classification’
prepareMutSig: no visible binding for global variable ‘OG_Hugo_Symbol’
prepareMutSig: no visible binding for global variable ‘Hugo_Symbol’
prepareMutSig: no visible global function definition for ‘.’
prepareMutSig: no visible binding for global variable ‘MutSig_Synonym’
prepareMutSig: no visible binding for global variable ‘N’
prepareMutSig: no visible global function definition for ‘write.table’
print_mat: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
print_mat: no visible global function definition for ‘par’
print_mat: no visible global function definition for ‘image’
print_mat: no visible global function definition for ‘rect’
print_mat : <anonymous>: no visible binding for global variable
  ‘temp_af’
print_mat : <anonymous> : <anonymous> : <anonymous>: no visible global
  function definition for ‘points’
print_mat: no visible global function definition for ‘abline’
print_mat: no visible global function definition for ‘mtext’
rainfallPlot: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
rainfallPlot: no visible global function definition for ‘.’
rainfallPlot: no visible binding for global variable ‘Chromosome’
rainfallPlot: no visible binding for global variable ‘Hugo_Symbol’
rainfallPlot: no visible binding for global variable ‘Start_Position’
rainfallPlot: no visible binding for global variable ‘End_Position’
rainfallPlot: no visible binding for global variable ‘Reference_Allele’
rainfallPlot: no visible binding for global variable
  ‘Tumor_Seq_Allele2’
rainfallPlot: no visible binding for global variable ‘Variant_Type’
rainfallPlot: no visible global function definition for
  ‘complete.cases’
rainfallPlot: no visible global function definition for ‘par’
rainfallPlot: no visible global function definition for ‘segments’
rainfallPlot: no visible global function definition for ‘points’
rainfallPlot: no visible global function definition for ‘axis’
rainfallPlot: no visible global function definition for ‘mtext’
rainfallPlot: no visible global function definition for ‘arrows’
rainfallPlot: no visible global function definition for ‘title’
rainfallPlot: no visible global function definition for ‘legend’
rainfallPlot: no visible global function definition for ‘dev.copy’
read.maf: no visible binding for global variable ‘Mutation_Status’
read.maf: no visible binding for global variable ‘Hugo_Symbol’
read.maf: no visible binding for global variable
  ‘Variant_Classification’
read.maf: no visible global function definition for ‘.’
read.maf: no visible binding for global variable ‘Tumor_Sample_Barcode’
read.maf: no visible binding for global variable ‘Unique_Name’
read.maf: no visible binding for global variable ‘Wide_Peak_Limits’
read.maf: no visible binding for global variable ‘id’
readGistic: no visible binding for global variable ‘Unique_Name’
readGistic: no visible binding for global variable ‘Wide_Peak_Limits’
readGistic: no visible binding for global variable ‘cytoband’
readGistic: no visible binding for global variable ‘value’
readGistic: no visible global function definition for ‘.’
readGistic: no visible binding for global variable ‘variable’
readGistic : <anonymous>: no visible binding for global variable
  ‘variable’
readGistic : <anonymous>: no visible binding for global variable
  ‘cytoband’
readGistic : <anonymous>: no visible binding for global variable
  ‘TumorSampleBarcode’
readGistic: no visible binding for global variable ‘CN’
readGistic: no visible binding for global variable ‘TumorSampleBarcode’
readGistic: no visible binding for global variable ‘Variant_Type’
readGistic: no visible binding for global variable ‘Cytoband’
readGistic: no visible binding for global variable ‘peakID’
readGistic: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
readGistic: no visible binding for global variable ‘qvalues’
readSegs: no visible binding for global variable ‘Chromosome’
readSegs: no visible binding for global variable ‘Start_Position’
readSegs: no visible binding for global variable ‘End_Position’
refineClusters: no visible binding for global variable ‘t_vaf’
repelPoints: no visible binding for global variable ‘pos’
repelPoints: no visible binding for global variable ‘distance’
repelPoints: no visible global function definition for ‘.’
run_surv: no visible binding for global variable ‘Group’
run_surv: no visible global function definition for ‘pchisq’
run_surv: no visible global function definition for ‘par’
run_surv: no visible global function definition for ‘abline’
run_surv: no visible global function definition for ‘points’
run_surv: no visible binding for global variable ‘Time’
run_surv: no visible binding for global variable ‘survProb’
run_surv: no visible global function definition for ‘lines’
run_surv: no visible global function definition for ‘axis’
run_surv: no visible global function definition for ‘mtext’
run_surv: no visible global function definition for ‘legend’
run_surv: no visible global function definition for ‘title’
sampleSwaps: no visible binding for global variable ‘id’
sampleSwaps: no visible binding for global variable ‘chr’
sampleSwaps: no visible binding for global variable ‘start’
sampleSwaps : <anonymous>: no visible global function definition for
  ‘.’
sampleSwaps : <anonymous>: no visible binding for global variable ‘id’
sampleSwaps : <anonymous>: no visible binding for global variable ‘ref’
sampleSwaps : <anonymous>: no visible binding for global variable ‘alt’
sampleSwaps : <anonymous> : <anonymous>: no visible binding for global
  variable ‘vaf’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘loci’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘ref_rc’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘alt_rc’
sampleSwaps : <anonymous>: no visible binding for global variable ‘vaf’
sampleSwaps: no visible binding for global variable ‘vaf’
sampleSwaps: no visible binding for global variable ‘total’
sampleSwaps: no visible binding for global variable ‘ref_rc’
sampleSwaps: no visible binding for global variable ‘alt_rc’
sampleSwaps: no visible global function definition for ‘complete.cases’
sampleSwaps : <anonymous> : <anonymous> : <anonymous>: no visible
  global function definition for ‘fisher.test’
sampleSwaps : <anonymous> : <anonymous> : <anonymous>: no visible
  binding for global variable ‘ref_rc’
sampleSwaps : <anonymous> : <anonymous> : <anonymous>: no visible
  binding for global variable ‘alt_rc’
sampleSwaps : <anonymous> : <anonymous>: no visible global function
  definition for ‘cor.test’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘XY_possibly_paired’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘fract_concordant_snps’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘cor_coef’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘X_bam’
sampleSwaps : <anonymous>: no visible binding for global variable
  ‘Y_bam’
sampleSwaps: no visible binding for global variable
  ‘XY_possibly_paired’
segmentLogR: no visible binding for global variable ‘contig’
segmentLogR: no visible binding for global variable ‘logR’
segmentLogR: no visible binding for global variable ‘pos’
segmentLogR: no visible global function definition for ‘write.table’
segmentLogR: no visible global function definition for ‘png’
setdiffMAF: no visible binding for global variable ‘Chromosome’
setdiffMAF: no visible binding for global variable ‘Start_Position’
setdiffMAF: no visible binding for global variable ‘End_Position’
setdiffMAF: no visible global function definition for ‘.’
setdiffMAF: no visible binding for global variable ‘Reference_Allele’
setdiffMAF: no visible binding for global variable ‘Tumor_Seq_Allele2’
setdiffMAF: no visible binding for global variable ‘variant_ID’
setdiffMAF: no visible binding for global variable ‘maf_slot’
shiftPoints: no visible binding for global variable ‘pos’
signatureEnrichment: no visible global function definition for ‘kmeans’
signatureEnrichment: no visible binding for global variable ‘Cluster’
signatureEnrichment: no visible binding for global variable ‘Signature’
signatureEnrichment : <anonymous>: no visible binding for global
  variable ‘Signature’
signatureEnrichment : <anonymous>: no visible binding for global
  variable ‘Tumor_Sample_Barcode’
signatureEnrichment : <anonymous>: no visible binding for global
  variable ‘sd’
signatureEnrichment : <anonymous>: no visible binding for global
  variable ‘N’
signatureEnrichment : add_legend: no visible global function definition
  for ‘par’
signatureEnrichment : add_legend: no visible global function definition
  for ‘legend’
signatureEnrichment: no visible global function definition for ‘par’
signatureEnrichment: no visible global function definition for
  ‘barplot’
signatureEnrichment: no visible global function definition for
  ‘segments’
signatureEnrichment: no visible global function definition for ‘axis’
signatureEnrichment: no visible global function definition for ‘mtext’
signatureEnrichment: no visible global function definition for ‘title’
signatureEnrichment: no visible global function definition for
  ‘boxplot’
signatureEnrichment: no visible global function definition for ‘.’
signatureEnrichment: no visible global function definition for ‘median’
signatureEnrichment: no visible binding for global variable ‘N’
signatureEnrichment: no visible global function definition for
  ‘write.table’
somaticInteractions: no visible binding for global variable
  ‘Hugo_Symbol’
somaticInteractions: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
somaticInteractions : <anonymous> : <anonymous>: no visible global
  function definition for ‘fisher.test’
somaticInteractions: no visible binding for global variable ‘pAdj’
somaticInteractions: no visible global function definition for
  ‘p.adjust’
somaticInteractions: no visible binding for global variable ‘pValue’
somaticInteractions: no visible global function definition for ‘.’
somaticInteractions: no visible binding for global variable ‘gene1’
somaticInteractions: no visible binding for global variable ‘gene2’
somaticInteractions: no visible binding for global variable
  ‘event_ratio’
somaticInteractions: no visible binding for global variable ‘01’
somaticInteractions: no visible binding for global variable ‘10’
somaticInteractions: no visible binding for global variable ‘11’
somaticInteractions: no visible binding for global variable ‘pair’
somaticInteractions: no visible binding for global variable
  ‘AlteredSamples’
somaticInteractions: no visible global function definition for ‘par’
somaticInteractions: no visible global function definition for ‘image’
somaticInteractions: no visible global function definition for ‘abline’
somaticInteractions: no visible global function definition for ‘mtext’
somaticInteractions: no visible binding for global variable ‘Event’
somaticInteractions: no visible global function definition for ‘text’
somaticInteractions: no visible global function definition for ‘points’
somaticInteractions: no visible global function definition for ‘axis’
sortByMutation: no visible binding for global variable ‘MutatedSamples’
sortByMutation: no visible binding for global variable ‘Hugo_Symbol’
subsetMaf: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
subsetMaf: no visible binding for global variable ‘Variant_Type’
subsetMaf: no visible binding for global variable ‘Hugo_Symbol’
subsetMaf: no visible binding for global variable ‘Chromosome’
subsetMaf: no visible binding for global variable ‘Start_Position’
subsetMaf: no visible binding for global variable ‘End_Position’
summarizeGistic: no visible binding for global variable ‘Hugo_Symbol’
summarizeGistic: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
summarizeGistic: no visible global function definition for ‘.’
summarizeGistic: no visible binding for global variable
  ‘Variant_Classification’
summarizeGistic: no visible binding for global variable ‘total’
summarizeGistic: no visible binding for global variable ‘median’
summarizeGistic: no visible binding for global variable ‘Cytoband’
summarizeMaf: no visible binding for global variable ‘Variant_Type’
summarizeMaf: no visible binding for global variable ‘Hugo_Symbol’
summarizeMaf: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
summarizeMaf: no visible global function definition for ‘.’
summarizeMaf: no visible binding for global variable
  ‘Variant_Classification’
summarizeMaf: no visible binding for global variable ‘total’
summarizeMaf: no visible binding for global variable ‘CNV_total’
summarizeMaf: no visible binding for global variable ‘median’
summarizeMaf: no visible binding for global variable ‘CNV’
summarizeMaf: no visible binding for global variable ‘MutatedSamples’
summarizeMaf: no visible binding for global variable ‘Mean’
summarizeMaf: no visible binding for global variable ‘Median’
survGroup: no visible binding for global variable ‘Hugo_Symbol’
survGroup: no visible global function definition for ‘combn’
survGroup: no visible binding for global variable ‘Time’
survGroup: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
survGroup: no visible binding for global variable ‘P_value’
tcgaCompare: no visible global function definition for ‘.’
tcgaCompare: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
tcgaCompare: no visible binding for global variable ‘total’
tcgaCompare: no visible binding for global variable ‘site’
tcgaCompare: no visible binding for global variable ‘cohort’
tcgaCompare : <anonymous>: no visible global function definition for
  ‘.’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘total’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘cohort’
tcgaCompare: no visible global function definition for
  ‘pairwise.t.test’
tcgaCompare: no visible binding for global variable ‘plot_total’
tcgaCompare: no visible binding for global variable ‘total_perMB’
tcgaCompare: no visible global function definition for ‘median’
tcgaCompare: no visible binding for global variable ‘V2’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘plot_total’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘TCGA’
tcgaCompare: no visible global function definition for ‘rect’
tcgaCompare: no visible global function definition for ‘par’
tcgaCompare: no visible global function definition for ‘abline’
tcgaCompare : <anonymous>: no visible binding for global variable ‘V3’
tcgaCompare : <anonymous>: no visible global function definition for
  ‘points’
tcgaCompare: no visible global function definition for ‘axis’
tcgaCompare: no visible binding for global variable
  ‘Median_Mutations_log10’
tcgaCompare: no visible binding for global variable ‘Median_Mutations’
tcgaCompare: no visible global function definition for ‘mtext’
tcgaCompare : <anonymous>: no visible global function definition for
  ‘segments’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘Median_Mutations_log10’
tcgaCompare : <anonymous>: no visible binding for global variable
  ‘Median_Mutations’
tcgaCompare: no visible binding for global variable ‘TCGA’
tcgaCompare: no visible binding for global variable ‘Pval’
tcgaDriverBP: no visible binding for global variable ‘Hugo_Symbol’
tcgaDriverBP: no visible global function definition for ‘.’
tcgaDriverBP: no visible binding for global variable ‘AlteredSamples’
tcgaDriverBP: no visible global function definition for ‘par’
tcgaDriverBP: no visible global function definition for ‘image’
tcgaDriverBP: no visible global function definition for ‘abline’
tcgaDriverBP: no visible global function definition for ‘points’
tcgaDriverBP: no visible global function definition for ‘mtext’
tcgaDriverBP: no visible global function definition for ‘text’
tcgaDriverBP: no visible global function definition for ‘title’
tcgaDriverBP : <anonymous>: no visible binding for global variable
  ‘Gene’
tcgaDriverBP: no visible binding for global variable ‘Cancer_type’
tcgaDriverBP: no visible binding for global variable ‘Pathway’
tcgaDriverBP: no visible binding for global variable ‘ID’
tcgaDriverBP: no visible binding for global variable ‘pctAltered’
tcgaDriverBP: no visible binding for global variable ‘tcga_driver’
titv: no visible binding for global variable ‘Reference_Allele’
titv: no visible binding for global variable ‘Tumor_Seq_Allele2’
titv: no visible binding for global variable ‘con’
titv: no visible global function definition for ‘.’
titv: no visible binding for global variable ‘Tumor_Sample_Barcode’
titv: no visible binding for global variable ‘N’
titv: no visible binding for global variable ‘con.class’
titv: no visible binding for global variable ‘fract’
titv: no visible binding for global variable ‘nVars’
titv: no visible binding for global variable ‘TiTv’
titv: no visible global function definition for ‘write.table’
tmb: no visible global function definition for ‘.’
tmb: no visible binding for global variable ‘Tumor_Sample_Barcode’
tmb: no visible binding for global variable ‘total’
tmb: no visible binding for global variable ‘total_perMB’
tmb: no visible binding for global variable ‘total_perMB_log’
tmb: no visible global function definition for ‘median’
tmb: no visible global function definition for ‘par’
tmb: no visible global function definition for ‘abline’
tmb: no visible global function definition for ‘points’
tmb: no visible global function definition for ‘title’
tmb: no visible global function definition for ‘axis’
tmb: no visible global function definition for ‘mtext’
transformSegments: no visible binding for global variable
  ‘Start_Position’
transformSegments: no visible binding for global variable
  ‘End_Position’
transformSegments: no visible binding for global variable ‘Chromosome’
trinucleotideMatrix: no visible binding for global variable ‘pkgname’
trinucleotideMatrix: no visible binding for global variable
  ‘Chromosome’
trinucleotideMatrix: no visible binding for global variable
  ‘Start_Position’
trinucleotideMatrix: no visible binding for global variable
  ‘End_Position’
trinucleotideMatrix: no visible binding for global variable ‘N’
trinucleotideMatrix: no visible binding for global variable ‘Start’
trinucleotideMatrix: no visible binding for global variable ‘End’
trinucleotideMatrix: no visible binding for global variable ‘upstream’
trinucleotideMatrix: no visible binding for global variable
  ‘downstream’
trinucleotideMatrix: no visible global function definition for ‘.’
trinucleotideMatrix: no visible binding for global variable ‘A’
trinucleotideMatrix: no visible binding for global variable ‘C’
trinucleotideMatrix: no visible binding for global variable ‘G’
trinucleotideMatrix: no visible binding for global variable
  ‘trinucleotide’
trinucleotideMatrix: no visible binding for global variable ‘updown’
trinucleotideMatrix: no visible binding for global variable ‘TCA’
trinucleotideMatrix: no visible binding for global variable ‘TCT’
trinucleotideMatrix: no visible binding for global variable ‘AGA’
trinucleotideMatrix: no visible binding for global variable ‘TGA’
trinucleotideMatrix: no visible binding for global variable ‘tcw’
trinucleotideMatrix: no visible binding for global variable ‘wga’
trinucleotideMatrix: no visible binding for global variable
  ‘Substitution’
trinucleotideMatrix: no visible binding for global variable
  ‘SubstitutionType’
trinucleotideMatrix: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
trinucleotideMatrix: no visible binding for global variable ‘n_A’
trinucleotideMatrix: no visible binding for global variable ‘A>C’
trinucleotideMatrix: no visible binding for global variable ‘A>G’
trinucleotideMatrix: no visible binding for global variable ‘A>T’
trinucleotideMatrix: no visible binding for global variable ‘n_T’
trinucleotideMatrix: no visible binding for global variable ‘T>A’
trinucleotideMatrix: no visible binding for global variable ‘T>C’
trinucleotideMatrix: no visible binding for global variable ‘T>G’
trinucleotideMatrix: no visible binding for global variable ‘n_G’
trinucleotideMatrix: no visible binding for global variable ‘G>A’
trinucleotideMatrix: no visible binding for global variable ‘G>C’
trinucleotideMatrix: no visible binding for global variable ‘G>T’
trinucleotideMatrix: no visible binding for global variable ‘n_C’
trinucleotideMatrix: no visible binding for global variable ‘C>A’
trinucleotideMatrix: no visible binding for global variable ‘C>G’
trinucleotideMatrix: no visible binding for global variable ‘C>T’
trinucleotideMatrix: no visible binding for global variable
  ‘n_mutations’
trinucleotideMatrix: no visible binding for global variable
  ‘SubstitutionMotif’
trinucleotideMatrix: no visible binding for global variable ‘tCw_to_A’
trinucleotideMatrix: no visible binding for global variable ‘T[C>A]A’
trinucleotideMatrix: no visible binding for global variable ‘T[C>A]T’
trinucleotideMatrix: no visible binding for global variable ‘tCw_to_G’
trinucleotideMatrix: no visible binding for global variable ‘T[C>G]A’
trinucleotideMatrix: no visible binding for global variable ‘T[C>G]T’
trinucleotideMatrix: no visible binding for global variable ‘tCw_to_T’
trinucleotideMatrix: no visible binding for global variable ‘T[C>T]A’
trinucleotideMatrix: no visible binding for global variable ‘T[C>T]T’
trinucleotideMatrix: no visible binding for global variable ‘tCw’
trinucleotideMatrix: no visible binding for global variable ‘wGa_to_C’
trinucleotideMatrix: no visible binding for global variable ‘A[G>C]A’
trinucleotideMatrix: no visible binding for global variable ‘T[G>C]A’
trinucleotideMatrix: no visible binding for global variable ‘wGa_to_T’
trinucleotideMatrix: no visible binding for global variable ‘A[G>T]A’
trinucleotideMatrix: no visible binding for global variable ‘T[G>T]A’
trinucleotideMatrix: no visible binding for global variable ‘wGa_to_A’
trinucleotideMatrix: no visible binding for global variable ‘A[G>A]A’
trinucleotideMatrix: no visible binding for global variable ‘T[G>A]A’
trinucleotideMatrix: no visible binding for global variable ‘wGa’
trinucleotideMatrix: no visible binding for global variable
  ‘tCw_to_G+tCw_to_T’
trinucleotideMatrix: no visible binding for global variable
  ‘APOBEC_Enrichment’
trinucleotideMatrix: no visible binding for global variable
  ‘n_C>G_and_C>T’
trinucleotideMatrix: no visible binding for global variable
  ‘non_APOBEC_mutations’
trinucleotideMatrix: no visible binding for global variable
  ‘fraction_APOBEC_mutations’
trinucleotideMatrix : <anonymous>: no visible global function
  definition for ‘fisher.test’
trinucleotideMatrix: no visible binding for global variable
  ‘fisher_pvalue’
trinucleotideMatrix: no visible binding for global variable ‘fdr’
trinucleotideMatrix: no visible global function definition for
  ‘p.adjust’
trinucleotideMatrix: no visible binding for global variable
  ‘APOBEC_Enriched’
trinucleotideMatrix: no visible binding for global variable
  ‘SubstitutionTypeMotif’
trinucleotideMatrix: no visible global function definition for
  ‘write.table’
vafCompare: no visible binding for global variable ‘Hugo_Symbol’
vafCompare: no visible binding for global variable ‘t_vaf’
vafCompare: no visible binding for global variable ‘t_alt_count’
vafCompare: no visible binding for global variable ‘t_ref_count’
vafCompare: no visible global function definition for ‘.’
vafCompare: no visible binding for global variable ‘Cohort’
vafCompare: no visible global function definition for ‘layout’
vafCompare: no visible global function definition for ‘par’
vafCompare: no visible global function definition for ‘boxplot’
vafCompare: no visible global function definition for ‘stripchart’
vafCompare: no visible global function definition for ‘axis’
vafCompare: no visible global function definition for ‘title’
vafCompare: no visible global function definition for ‘abline’
vafCompare: no visible global function definition for ‘t.test’
vafCompare: no visible global function definition for ‘text’
validateMaf: no visible binding for global variable ‘variantId’
validateMaf: no visible binding for global variable ‘Chromosome’
validateMaf: no visible binding for global variable ‘Start_Position’
validateMaf: no visible binding for global variable
  ‘Tumor_Sample_Barcode’
validateMaf: no visible binding for global variable ‘Reference_Allele’
validateMaf: no visible binding for global variable ‘Tumor_Seq_Allele2’
validateMaf: no visible binding for global variable ‘Hugo_Symbol’
validateMaf: no visible binding for global variable
  ‘Variant_Classification’
validateMaf: no visible binding for global variable ‘Variant_Type’
validateMaf: no visible binding for global variable ‘End_Position’
write.GisticSummary: no visible global function definition for
  ‘write.table’
write.mafSummary: no visible global function definition for
  ‘write.table’
Undefined global functions or variables:
  . 01 10 11 A A>C A>G A>T AAChange AAChange.refGene AAChange_ AGA
  APOBEC_Enriched APOBEC_Enrichment A[G>A]A A[G>C]A A[G>T]A Alt
  AlteredSamples Amp Analysis C C>A C>G C>T CN CNV CNV_total
  Cancer_type Chromosome Cluster Cohort Cytoband Del Description
  DomainLabel End End_Position End_Position_updated Entrez
  Entrez_Gene_Id Event ExonicFunc.refGene Feature_1 Feature_2
  Fraction_mutated_samples Freq Func.refGene G G>A G>C G>T G_Score Gene
  Gene.refGene Genotype Group Group1 Group2 HGNC Hugo_Symbol ID Ins
  Label MATH Mean Median Median_Mutations Median_Mutations_log10
  MutSig_Synonym MutatedSamples MutatedSamples_m1 MutatedSamples_m2
  Mutated_samples Mutation_Status N N.x N.y OG_Hugo_Symbol OR OR_high
  OR_low P_value Pathway Pval Ref Reference_Allele Sample SampleSize
  Segment_End Segment_Mean Segment_Start Signature Size Start
  Start_Position Start_Position_updated Substitution SubstitutionMotif
  SubstitutionType SubstitutionTypeMotif T>A T>C T>G TCA TCGA TCT TGA
  T[C>A]A T[C>A]T T[C>G]A T[C>G]T T[C>T]A T[C>T]T T[G>A]A T[G>C]A
  T[G>T]A TiTv Time TumorSampleBarcode Tumor_Sample_Barcode
  Tumor_Seq_Allele2 Unique_Name V1 V2 V3 VAF VC Var1 Var2
  Variant_Classification Variant_Classification_temp Variant_Type
  Wide_Peak_Limits XY_possibly_paired X_bam Y_bam aa.length abline
  adjPval alt alt_rc amp anno_Position arrows assembly_version axis baf
  barplot bg box boxStat boxplot browseURL category cf chr chromosome
  chromosome_end chromosome_start ci.low ci.up cohort colorRampPalette
  combn complete.cases con con.class consequence_type contig conv
  cophenetic cor.test cor_coef count count2 cytoband dbinom density
  dev.copy distance doc doc_n doc_norm doc_t domainCol domain_lenght
  download.file downstream dp endDist ens_id event_ratio fdr
  fisher.test fisher_pvalue fract fractMutated fract_concordant_snps
  fract_muts_in_clusters fraction fraction_APOBEC_mutations
  fraction_affected fs g1_muts g1_title g1_tot g2_muts g2_title g2_tot
  gene1 gene2 gene_affected gistic glm head heat.colors hgnc_symbol
  i.End_Position i.Start_Position icgc_sample_id id idx image kmeans
  lab labThis label layout legend lines loc loci logR log_fdr log_q
  lower maf_slot max_alt median mtext mutated_from_allele
  mutated_to_allele mutload muts_in_clusters n nGenes nMut nMuts nVars
  n_A n_C n_C>G_and_C>T n_G n_T n_affected_genes n_mutated_Feature
  n_mutated_Feature1 n_mutated_Feature2 n_mutated_group1
  n_mutated_group2 n_mutations na.omit nonApobec non_APOBEC_mutations
  or or_new p.adjust pAdj pValue p_value pair pairwise.t.test
  pairwise.table par pchisq pctAltered pct_alt peakID pfam pie pkgname
  plot.new plot_total png pnorm points poisson poisson.test poissonFdr
  pos pos2 posRounded protein.ID pval qf qnorm qvalues read.csv rect
  ref ref_alt ref_alt_diff ref_alt_len ref_rc reference_genome_allele
  refseq.ID row_id row_idx rug runif sd segments sequencing_strategy
  setTxtProgressBar significant site start startDist statFontSize
  stripchart survProb symbols t.test tCw tCw_to_A tCw_to_G
  tCw_to_G+tCw_to_T tCw_to_T tFdr t_alt_count t_depth t_ref_count t_vaf
  tcga_driver tcw temp_af text th title tot tot_depth total total_perMB
  total_perMB_log trinucleotide txtProgressBar unit updown upper
  upstream vaf value variable variantId variant_ID
  verification_platform verification_status wGa wGa_to_A wGa_to_C
  wGa_to_T wga wilcox.test write.table ystart
Consider adding
  importFrom("grDevices", "colorRampPalette", "dev.copy", "heat.colors",
             "png")
  importFrom("graphics", "abline", "arrows", "axis", "barplot", "box",
             "boxplot", "image", "layout", "legend", "lines", "mtext",
             "par", "pie", "plot.new", "points", "rect", "rug",
             "segments", "stripchart", "symbols", "text", "title")
  importFrom("stats", "C", "complete.cases", "cophenetic", "cor.test",
             "dbinom", "density", "fisher.test", "glm", "kmeans",
             "median", "na.omit", "p.adjust", "pairwise.t.test",
             "pairwise.table", "pchisq", "pnorm", "poisson",
             "poisson.test", "qf", "qnorm", "runif", "sd", "start",
             "t.test", "wilcox.test")
  importFrom("utils", "browseURL", "combn", "download.file", "head",
             "read.csv", "setTxtProgressBar", "txtProgressBar",
             "write.table")
to your NAMESPACE file.
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking line endings in C/C++/Fortran sources/headers ... OK
* checking line endings in Makefiles ... OK
* checking compilation flags in Makevars ... OK
* checking for GNU extensions in Makefiles ... NOTE
GNU make is a SystemRequirements.
* checking for portable use of $(BLAS_LIBS) and $(LAPACK_LIBS) ... OK
* checking use of PKG_*FLAGS in Makefiles ... OK
* checking compiled code ... NOTE
Note: information on .o files is not available
File ‘/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/maftools/libs/maftools.so’:
  Found ‘___assert_rtn’, possibly from ‘assert’ (C)
  Found ‘___stderrp’, possibly from ‘stderr’ (C)
  Found ‘___stdoutp’, possibly from ‘stdout’ (C)
  Found ‘_abort’, possibly from ‘abort’ (C)
  Found ‘_exit’, possibly from ‘exit’ (C)

Compiled code should not call entry points which might terminate R nor
write to stdout/stderr instead of to the console, nor use Fortran I/O
nor system RNGs nor [v]sprintf. The detected symbols are linked into
the code but might come from libraries and not actually be called.

See ‘Writing portable packages’ in the ‘Writing R Extensions’ manual.
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
          user system elapsed
maf2mae 32.204  0.645  38.529
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 6 NOTEs
See
  ‘/Users/biocbuild/bbs-3.20-bioc/meat/maftools.Rcheck/00check.log’
for details.

Installation output

maftools.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL maftools
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library’
* installing *source* package ‘maftools’ ...
** using staged installation
** libs
using C compiler: ‘Apple clang version 14.0.0 (clang-1400.0.29.202)’
using SDK: ‘MacOSX11.3.sdk’
clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -D_FILE_OFFSET_BITS=64 -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/Rhtslib/include' -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/zlibbioc/include' -I/opt/R/x86_64/include    -fPIC  -falign-functions=64 -Wall -g -O2  -c ntcounts.c -o ntcounts.o
clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -D_FILE_OFFSET_BITS=64 -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/Rhtslib/include' -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/zlibbioc/include' -I/opt/R/x86_64/include    -fPIC  -falign-functions=64 -Wall -g -O2  -c snpcounts.c -o snpcounts.o
clang -arch x86_64 -I"/Library/Frameworks/R.framework/Resources/include" -DNDEBUG -D_FILE_OFFSET_BITS=64 -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/Rhtslib/include' -I'/Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/zlibbioc/include' -I/opt/R/x86_64/include    -fPIC  -falign-functions=64 -Wall -g -O2  -c somaticfreq.c -o somaticfreq.o
clang -arch x86_64 -dynamiclib -Wl,-headerpad_max_install_names -undefined dynamic_lookup -L/Library/Frameworks/R.framework/Resources/lib -L/opt/R/x86_64/lib -o maftools.so ntcounts.o snpcounts.o somaticfreq.o /Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/Rhtslib/usrlib/libhts.a -lcurl -lbz2 -llzma -lz -F/Library/Frameworks/R.framework/.. -framework R -Wl,-framework -Wl,CoreFoundation
installing to /Library/Frameworks/R.framework/Versions/4.4-x86_64/Resources/library/00LOCK-maftools/00new/maftools/libs
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** checking absolute paths in shared objects and dynamic libraries
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (maftools)

Tests output

Example timings

maftools.Rcheck/maftools-Ex.timings

name	user	system	elapsed
MAF	0.412	0.079	0.577
annovarToMaf	0.267	0.040	0.396
clinicalEnrichment	0.000	0.001	0.000
coBarplot	0.697	0.039	0.893
coGisticChromPlot	0.000	0.001	0.001
coOncoplot	0.695	0.040	0.900
drugInteractions	0.826	0.091	1.079
estimateSignatures	0.001	0.000	0.001
extractSignatures	0.000	0.000	0.001
filterMaf	1.684	0.063	2.086
forestPlot	0.569	0.024	0.679
genesToBarcodes	0.714	0.030	0.929
genotypeMatrix	0.679	0.024	0.826
getClinicalData	0.651	0.018	0.782
getCytobandSummary	1.206	0.032	1.502
getFields	0.671	0.023	0.758
getGeneSummary	0.669	0.026	0.753
getSampleSummary	0.689	0.024	0.774
gisticBubblePlot	1.278	0.018	1.399
gisticChromPlot	1.496	0.032	1.737
gisticOncoPlot	1.200	0.023	1.423
icgcSimpleMutationToMAF	0.126	0.013	0.160
inferHeterogeneity	0.001	0.001	0.001
lollipopPlot	1.473	0.035	1.813
lollipopPlot2	2.043	0.039	2.413
maf2mae	32.204	0.645	38.529
mafCompare	0.495	0.030	0.642
mafSummary	1.319	0.086	1.671
mafSurvGroup	0.782	0.024	0.946
mafSurvival	0.732	0.023	0.872
mafbarplot	0.652	0.020	0.773
math.score	0.658	0.021	0.787
mutCountMatrix	1.293	1.689	3.743
oncodrive	2.619	0.055	3.152
oncoplot	1.871	0.035	2.182
oncostrip	0.757	0.040	0.860
pathways	1.280	0.037	1.516
pfamDomains	1.750	0.049	2.004
plotApobecDiff	0.001	0.000	0.001
plotCBSsegments	0.065	0.003	0.080
plotClusters	0	0	0
plotOncodrive	2.671	0.061	3.180
plotPathways	1.391	0.027	1.583
plotProtein	1.508	0.016	1.708
plotTiTv	0.875	0.035	1.029
plotVaf	0.676	0.023	0.866
plotmafSummary	0.777	0.021	0.894
prepareMutSig	0.804	0.039	0.919
read.maf	0.647	0.022	0.737
readGistic	1.180	0.020	1.323
setMaf	0.889	0.023	1.060
somaticInteractions	1.125	0.034	1.555
subsetMaf	1.349	0.037	1.688
survGroup	1.342	0.037	1.684
tcgaAvailable	0.037	0.015	0.363
tcgaCompare	1.880	0.081	2.351
tcgaLoad	0.269	0.024	1.064
titv	0.932	0.028	1.124
tmb	0.607	0.021	0.807
trinucleotideMatrix	0.000	0.001	0.001
write.GisticSummary	1.291	0.040	1.636
write.mafSummary	0.655	0.024	0.763